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Patients are often unsure what this is, and the honest answer reassures them: it is a signal that wakes the skin's own repair, nothing borrowed, nothing foreign in its effect. It does not fill or freeze. It simply reminds the tissue how to mend itself. I find that the body, asked kindly, remembers a great deal.Dr Dana Beiki
About this treatment
Polynucleotides are bio-regenerative injections that stimulate your skin’s natural repair mechanisms at a cellular level. Derived from purified DNA fragments, they activate fibroblasts to produce new collagen and elastin while improving hydration, elasticity, and tissue quality. The result is skin that looks and feels genuinely healthier, not just treated.
The science
Purified polynucleotide solution is injected into the dermis using fine needles. Once in the tissue, the DNA fragments activate fibroblast cells, triggering a cascade of repair: new collagen synthesis, improved elastin production, enhanced hydration, and reduced oxidative stress. The effect is cumulative over a course of treatments.
How it’s priced
Each area is priced on its own, so you treat only what you came for. A course is what Dr Beiki recommends over a single session: the results are cumulative, so a course builds and holds, while a single session is a top-up or a first trial. He will advise the areas and the number of sessions that genuinely serve you, never more. The £75 consultation is fully redeemable against any treatment booked.
By area & course
The most useful thing a clinic can tell you is whether a treatment is wrong for you. Here is who tends to do well, and where Dr Beiki would send you elsewhere. He would rather lose the booking than do the wrong thing.
Made for
Where it isn’t the answer
Some faces are better served by a different treatment, and Dr Beiki will tell you plainly if yours is one of them. He will not recommend something that will not serve you.
The real effect of polynucleotides is often quieter, and more interesting, than the obvious one. Here is what is actually happening.

Purified polynucleotide solution is injected into the dermis using fine needles. Once in the tissue, the DNA fragments activate fibroblast cells, triggering a cascade of repair: new collagen synthesis, improved elastin production, enhanced hydration, and reduced oxidative stress. The effect is cumulative over a course of treatments.


The real measure
The aim is always the same: you, looking rested and like yourself, the better version of a good day, never overdone.

The questions clinics avoid are often the ones that decide whether you book. So we put them here, before you ask.
It will not add volume. If you are hoping for a plumper cheek or a fuller under-eye, this is the wrong tool.
It will not show its hand in a week. The regeneration unfolds over eight to twelve weeks as new collagen builds.
It will not work as a single session for most skin. The course of two or three is how the biology is designed to respond.
It will not replace sleep, water, or sun protection. It supports a skin that is being cared for elsewhere.
Every plan starts with Dr Beiki looking at your face. You choose how: free and online through Le Cabinet, or in person at the Bath clinic.
Free · online · no appointment
The private web app we give every patient, free. The four things that make it unlike any clinic app you have used:
Your plan
Anti-wrinkle
3 areas
Profhilo
2 sessions
Review
12 weeks

£75 · 45 minutes · redeemable
Forty-five minutes with Dr Beiki to examine your skin, answer your questions and agree your plan in person. The £75 is fully redeemable against any treatment booked on the day.

Polynucleotides give the skin's own repair cells better materials to work with. No more, and no less.
« My first ever time getting anti-wrinkle treatment, after having filler elsewhere, and the experience was night and day. Dana explained everything and listened to me. I felt very looked after and it didn't hurt a bit. »
Anti-wrinkle · Bath· Verified on Google
Some results build best over a sequenced course. These programmes fold this into a considered plan, priced a little below the same visits booked one at a time.
However you begin, it starts with a conversation.
Book a consultation with Dr Beiki, or start free with an online assessment in your own time.
Rated 5.0 on Google · 22 reviews
£75 with Dr Beiki, fully redeemable against your first treatment. The assessment is free.
Or pay in 3 interest-free with Klarna at checkout. 18+, T&Cs apply.
Goodlight Wellness Center · Bath